众文网1.一篇成功的meta分析论文有哪些良好的基础构建
谈谈我在科研文案这条路上（帮很多人写过）总结出来的一点心得经验：
一：选题
一个好的选题就成功了一半。选题大小决定了工作量大小，选题的争议性、新颖性、临床实用性决定了题目的价值，也决定了以后文章投稿的难易程度。
二：文献检索
检索一般强调查准率与查全率。两者矛盾，但meta分析要求查全要高，所以检索制定要合适。既不能让初筛文章太多，工作量太大，也不能遗漏重要文献。
三：数据提取
两个平行进行，尽量不进行讨论，等数据提取完后，由第三方确认或讨论解决。
四：数据处理
目前用的较多软件：STATA,REVMAN， 以及诊断性meta的meta-disc。
五：文章写作
严格按照相应的指南与手册进行。如RCT meta的PRISM，观察性研究的MOOSE等。
2.如何撰写高质量的Meta分析论文
只有确定好了主题。
才好动笔。还有人说，“确定一个好的主题，等于完成论文工作的一半” 。
因此，确定论文主题是撰写论文的第一要务。 ，再到现在的“以人为本”的过程。
现在，你写文章讲教学观，就要讲以人为本，以学生为本，千万不要讲以知识为本位。二是角度要新。
就是说，论文选题的角度要别具一格。“一树梅花万首诗”，“横看成岭侧成峰，远近高低各不同” ，讲的就是观察事物的新视角。
选题同样有个角度问题、找切入点的问题。同样的问题，同样的材料，不同人来选就有不同的感受、不同的主题。
3.meta分析论文所用文献的评分标准有哪些阿
Introduction 1 State the marker examined, the study objectives, and any prespecified hypotheses.Materials and methodsPatients2 Describe the characteristics (e.g. disease stage or comorbidities) of the study patients, including their source and inclusion and exclusion criteria. 3 Describe treatments received and how chosen (e.g. randomized or rule-based). Specimen characteristics4 Describe type of biological material used (including control samples) and methods of preservation and storage.Assay methods5 Specify the assay method used and provide (or reference) a detailed protocol, including specific reagents or kits used, quality control procedures, reproducibility assessments, quantitation methods, and scoring and reporting protocols. Specify whether and how assays were performed blinded to the study endpoint.Study design6 State the method of case selection, including whether prospective or retrospective and whether stratification or matching (e.g. by stage of disease or age) was used. Specify the time period from which cases were taken, the end of the follow-up period, and the median follow-up time. 7 Precisely define all clinical endpoints examined. 8 List all candidate variables initially examined or considered for inclusion in models. 9 Give rationale for sample size; if the study was designed to detect a specified effect size, give the target power and effect size. Statistical analysis methods10 Specify all statistical methods, including details of any variable selection procedures and other model-building issues, how model assumptions were verified, and how missing data were handled. 11 Clarify how marker values were handled in the analyses; if relevant, describe methods used for cutpoint determination.ResultsData 12 Describe the flow of patients through the study, including the number of patients included in each stage of the analysis (a diagram may be helpful) and reasons for dropout. Specifically, both overall and for each subgroup extensively examined report the numbers of patients and the number of events.13 Report distributions of basic demographic characteristics (at least age and sex), standard (disease-specific) prognostic variables, and tumor marker, including numbers of missing values. Analysis and presentation 14 Show the relation of the marker to standard prognostic variables.15 Present univariate analyses showing the relation between the marker and outcome, with the estimated effect (e.g. hazard ratio and survival probability). Preferably provide similar analyses for all other variables being analyzed. For the effect of a tumor marker on a time-to-event outcome, a Kaplan–Meier plot is recommended. 16 For key multivariable analyses, report estimated effects (e.g. hazard ratio) with confidence intervals for the marker and, at least for the final model, all other variables in the model. 17 Among reported results, provide estimated effects with confidence intervals from an analysis in which the marker and standard prognostic variables are included, regardless of their statistical significance. 18 If done, report results of further investigations, such as checking assumptions, sensitivity analyses, and internal validation.Discussion19 Interpret the results in the context of the prespecified hypotheses and other relevant studies; include a discussion of limitations of the study. 20 Discuss implications for future research and clinical value.。
4.如何撰写高质量的Meta分析论文
只有确定好了主题。
才好动笔。还有人说，“确定一个好的主题，等于完成论文工作的一半” 。
因此，确定论文主题是撰写论文的第一要务。 ，再到现在的“以人为本”的过程。
现在，你写文章讲教学观，就要讲以人为本，以学生为本，千万不要讲以知识为本位。二是角度要新。
就是说，论文选题的角度要别具一格。“一树梅花万首诗”，“横看成岭侧成峰，远近高低各不同” ，讲的就是观察事物的新视角。
选题同样有个角度问题、找切入点的问题。同样的问题，同样的材料，不同人来选就有不同的感受、不同的主题。
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